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NNMT overexpression is associated with obesity and insulin resistance

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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

Paraesthesia, balance problems, or cognitive difficulties may persist despite normalising blood counts

Annu Rev Cell Dev Biol 35:477500