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Furthermore, increased serum zonulin has been reported in many conditions associated with chronic, low grade mucosal barrier damage, including autoimmune diseases, diabetes, obesity, neurological and cognitive impairments, ageing, and cancer [240,241,242,243,244,245,246,247,248,249,250]

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External factors or environmental conditions, such as pH and temperature, can also affect the stability of dispersions and should therefore be controlled in experimental set-ups

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T4 medications like levothyroxine can work well for many thyroid patients when delivered properly, so do not dismiss T4 entirely just because the oral form has not worked for you