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However, starting later (2-4 weeks post-fracture) still beneficial for remodeling phase

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If you use it for general wellness , the effects might be more subtle and short-term unless combined with consistent treatments

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TJ proteins respond to a variety of stimuli including changes in diet, dysbiosis, viruses, inflammation, antibiotic treatment, and/or humoral or neuronal signals [10][1][4]

Responsible prescribing means proper patient selection, evidence-informed dosing, baseline and follow-up lab monitoring where appropriate, documented informed consent, and clinical follow-up to assess response