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These results suggest that an HFD causes severe abnormal mitochondrial morphology and dysfunction, while antioxidants and dietary restriction protect mitochondria and reduce oxidative stress in obesity-related nephropathy

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Marzullo L

A mitochondria-targeted covalent organic framework (COF) prodrug that is selectively activated by high intramitochondrial GSH levels was shown to trigger catalase collapse within the organelle, thereby amplifying local chemodynamic therapy (CDT) through enhanced ROS accumulation and mitochondrial dysfunction

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Association between serum ferritin level and fibromyalgia syndrome

2009;3:e478