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As shown in Fig S5B, this precursor was found in the lysosome-containing fraction and in the cytosol, consistent with a mechanism wherein it is generated in the lysosome and then transported into the cytoplasm for further processing into mature miR-4488

The therapeutic applications of these inhibitors, particularly the pan-inhibitors, have been extensively studied in various diseases

observed disrupted sinusoidal endothelium structure at 24 h post-HTx, suggesting endothelial disruption permits transplanted cell entrance into liver parenchyma (Figure 2)

10.1016/j.celrep.2020.107908 Cell Rep

Further studies are warranted to clarify the facilitating efficacy of melatonin on benzodiazepine withdrawal

Koster, R