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Description
Recently, the results of a landmark randomized controlled trial showed treatment with tirzepatide (15 mg subcutaneous/week), a dual GLP-1R/GIP receptor (GIPR) agonist, caused an 18% placebo-subtracted weight loss (21% total weight loss) at 72 weeks in people with obesity (6)
Medrano S, Burns-Cusato M, Atienza MB, Rahimi D, Scrable H
There are several theories regarding underlying mechanisms
J Biotechnol 214:6368
& Loff, S
Antioxidants 10, 197
