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The selective mGlu2/3 receptor agonist LY354740 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal

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As previously discussed, RMECs are highly sensitive to ferroptosis under pathological conditions, as they poorly upregulate GPX4 and SLC7A11, while RPE cells resist ferroptosis via upregulating FTH1 and activating the Nrf2 antioxidant pathway (154)

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