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Description
MASH, metabolic dysfunctionassociated steatohepatitis

Hepatic fat mobilisation resumes at the next scheduled dose

Studies show core biological changes, including reduced NK cell function, activation of the NLRP3 inflammasome, altered interferon and cytokine signaling, and evidence of mitochondrial and metabolic dysfunction (lactate/pyruvate, haptoglobin)

Corresponding fatty acid analyses revealed large shifts in the composition of the bkd strain depending on the supplied precursor (Fig 1B and Appendix Fig S1B)
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