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doi: 10.1210/me.2004-0215 24 25 26 KimJHongSJLimEKYuYSKimSWRohJHet al

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Multiple human and animal studies confirm that AOD-9604 has zero impact on fasting glucose, fasting insulin, HbA1c, IGF-1, cortisol, or thyroid hormones

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Crucially, this worked at extremely low concentrations picomolar to nanomolar suggesting high biological potency