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Lipid peroxidation can be triggered by non-enzymatic and enzymatic mechanisms

5.3 Ferroptosis and neuroinflammatory plaques 5.3.1 Microglial cells Microglia, the resident immune cells of the central nervous system, constitute approximately 1012% of total brain cells and play a significant role in maintaining immune surveillance and neural homeostasis ( in vivo studies support a neuroprotective role for activated microglia, evidence from ex vivo or cultured microglial models suggests these cells may also exhibit neurotoxic potential

Biotransformation in review: Applications in ocular disease and drug design

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Accordingly, we hypothesized that an exogenous supply of glycine and cysteine might lead to increased GSH synthesis in vivo , as well as the maintenance of the levels of metabolism of these essential amino acids

Perspective: L-arginine and L-citrulline Supplementation in Pregnancy: A Potential Strategy to Improve Birth Outcomes in Low-Resource Settings