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Studies have demonstrated that the protective effects of H 2 S against VILI are mediated through multiple pathways, including induction of cyclooxygenase-2 and its product prostaglandin J2 and their downstream effects [379]

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In vivo treatments Pregnant or nursing dams were injected intraperitoneally once a day with BPTES (100 mg/kg) or vehicle (5% DMSO in PBS) from E15.5 till birth or beginning on post-natal day 1 until post-natal day 10