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[DOI] [PubMed] [Google Scholar] 121.Park H.-S., Kim M.-J., Yu J.-H., Shin K.-S
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In its role as a coenzyme, NAD+ acts as a substrate that is irreversibly degraded by NAD+-consuming enzymes, including the SIRTs, PARPs, and CD38
Molecules 22 (6), 114
In summary, engineered extracellular vesicles, through precise functional design, show significant advantages in improving targeting, optimizing drug loading, and enhancing therapeutic effects, providing new technological pathways for the treatment of intervertebral disc degeneration
Anti-Inflammatory Properties: The activation of SIRT1 by increased NAD+ levels contributes to anti-inflammatory effects
