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While octadecapentaenoic acid (ODPA) can be observed in some alga (e.g., dinoflagellates), 72 it is generally not observed in mammals and ODPA-derived octadecanoids will not be discussed here

These can include: Nausea, Vomiting, Diarrhea, Stomach upset or pain, Bloating, Headache, Skin rash or allergic reactions (itching, hives, swelling), Fatigue

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10.1016/j.jep.2024.117923 181 WuZ.ChenT.QianY.LuoG.LiaoF.HeX.et al (2023b)

Whats most exciting about the new understanding of the power of the Antioxidant Enzymes is that specific phytochemicals can switch on that part of the DNA which codes for these and other cell-protective endogenous compounds