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This increase in PGC-1 regulates the cellular response to oxidative stress and significantly boosts the gene expression of various antioxidant enzymes such as SOD and GPX1 [36]

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Thus, it is widely accepted that low levels of GABA are responsible for the hyperexcitability of neurons [29]

PLoS ONE 8 , e75548 (2013)

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Oxidative stress through the production of free radicals does have some potentially beneficial effects for the host in terms of antibacterial action, immune defense, and signal transduction
