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J., Tschume, L

7.3 Development of combined intervention strategies The revised section now discusses the potential of combined therapeutic approaches, such as the co-administration of natural bioactive compounds with probiotics or prebiotics, to synergistically regulate gut microbiota composition, restore intestinal barrier integrity, and reduce hepatic oxidative stress and inflammation

& Rose, J

Pirfenidone Plus Inhaled N-Acetylcysteine for Idiopathic Pulmonary Fibrosis: a Randomised Trial

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63 Although adjuvant treatments like estrogen administration and physical barriers may offer short-term benefits, retrospective studies have shown that even with multiple surgeries combined with drug interventions, the live birth rate in severe cases remains below 40%, highlighting the limited regenerative potential of TCRA in advanced disease
