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Evoked pain encompasses allodynia which, is a painful perception in response to non-noxious stimuli and hyperalgesia, which is an exaggerated response to a noxious stimulus [2]

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As an important indicative point, prostaglandins were introduced at that time as the first mediators of cytoprotection

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It plays a key role in the metabolism of fatty acids and amino acids, supporting normal energy production at the cellular level.* Nervous system function Methylcobalamin is critical for the maintenance of the myelin sheath the protective coating around nerve fibres supporting healthy nerve conduction and normal neurological function.* Methylation & homocysteine metabolism B12 is a key cofactor in the methylation cycle, the biochemical pathway responsible for converting homocysteine to methionine

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[5] Pyridoxine (vitamin B) is converted to pyridoxal-5-phosphate, a coenzyme for over 100 enzymes in amino acid metabolism

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