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however, it can also create a reductive microenvironment that paradoxically may aid advanced tumors, reflecting the complex dual role of Nrf2 in cancer

Because the uncatalysed dismutation reaction for superoxide requires two superoxide molecules to react with each other, the dismutation rate is second-order with respect to initial superoxide concentration
Kasischke, K

There is no one size that fits all

doi: 10.1016/j.freeradbiomed.2019.06.008 39 MenonRBehniaFPolettiniJRichardsonLS

A literature review looking specifically at inhaled GSH determined that it has potential as a treatment for cystic fibrosis (CF), chronic otitis media with effusion (OME), HIV seropositive individuals, IPF, and chronic rhinitis [40]
