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Early microarray studies provided the first genome-wide snapshots of age-associated changes in gene expression, whereas the adoption of bulk RNA-seq enabled more comprehensive and less assumption-driven discovery, including detection of low-abundance transcripts and isoform-level regulation

However, the effects of berberine on neurodegenerative diseases are rarely reported and further investigation is still needed

The trial lasted for 3 months

(High-dose intravenous glutathione in man

They employ Trx more effectively than GSH to decrease H 2 O 2 and organic peroxides

The authors thank Christopher Quinn from English Consulting Brazil for the English revision