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Image credits: dodotone/Adobe Stock (Not the actual photo) Applegate has said she initially noticed subtle symptoms, including problems with balance, numbness in her limbs, and subtle tingling in her toes, but attributed them to fatigue before learning the devastating truth

Figure 4: Changes in body weight in A) lean mice and B) obese mice and changes in food intake in C) lean mice and D) obese mice, across the three different experimental treatment groups

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