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When inactive, AhR is localized to the cytoplasm (Noakes, 2015)

Mizera and Lieske have rooted their careers on a philosophy that goes beyond conventional care: combining the precision of modern medicine with evidence-based nutrition, exercise, sleep, and lifestyle optimization

Antioxidant activity modulated by polyphenol contents in apple and leaves during fruit development and ripening

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Thus, the extent to which allantoin acts as a direct reductant instead of an activator of plant antioxidant systems remains unclear

Since then, MTHFR and other folate-related gene variants have been implicated in a wide array of multifactorial disorders, including cardiovascular disease, cancer, psychiatric illness, and reproductive complications (see Figure 1 )