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Abbreviations ALSFRS-R: Revised amyotrophic lateral sclerosis functional rating scale CSF: Cerebrospinal fluid Cys: Cysteine GSH: Reduced glutathione GSH*: Glycine- 13 C 2 , 15 N-Glutathione tGSH: Total glutathione GS-NEM: Derivatisation of GSH by NEM tGS-NEM: Derivatisation of tGSH by NEM GSSG: Oxidised glutathione HC: Healthy control group HPLC: High-pressure liquid chromatography ALS: Amyotrophic lateral sclerosis MRM: Multiple reaction monitoring MS: Mass spectrometry NEM: N-Ethylmaleimide TCEP: Tris(2-carboxyethyl)phosphine References Barber SC, Mead RJ, Shaw PJ

[DOI] [PubMed] [Google Scholar] Dickstein LP, Liow JS, Austermuehle A, Zoghbi S, Inati SK, Zaghloul K, Zanotti-Fregonara P, Theodore WH (2019) Neuroinflammation in neocortical epilepsy measured by PET imaging of translocator protein

Some individuals genetically predisposed to robust healing responses while others heal slowly regardless of interventions

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L-Carnitine AND Sirt3/Nrf2