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Consistent with previous reports, Hippo signaling is known to regulate epithelial tissue reprogramming 50 and cooperate with paired box protein Pax-3 to modulate MITF expression in neural crest cells, thereby influencing melanocyte fate specification 51

Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis

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Citation on PubMed Mahle WT, Newburger JW, Matherne GP, Smith FC, Hoke TR, Koppel R, Gidding SS, Beekman RH 3rd, Grosse SD