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Impact on Mitochondrial Bioenergetics and ROS Generation Hepatocellular mitochondria are the primary targets of ethanol-induced toxicity, as they are central to fatty acid -oxidation and energy production [40]

The mitochondrial matrix is the space delimited by the inner membrane and contains the pyruvate dehydrogenase complex and the enzymes of the tricarboxylic acid cycle (TCA), the fatty acid oxidation, and the oxidation of amino acids [21] (Figure 6)

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Semaglutide an incretin mimetic

[DOI] [PMC free article] [PubMed] [Google Scholar] [43].Park J, Choi H, Min JS, Park SJ, Kim JH, Park HJ, et al