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Description
The therapeutic potential for GGC to increase GSH is related to the second GSH biosynthetic enzyme, glutathione synthetase (GS) which is not regulated by non-allosteric feedback inhibition by GSH

One pathway creates NAPQIa reactive compound that needs to be neutralized quickly

[PMC free article: PMC5451581] [PubMed: 28314764] 94

H., Biebl, M
This means decisions about supplementation remain largely based on mechanistic plausibility and practitioner experience rather than randomized controlled evidence

Chemosphere, 375 , 144226
