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19 Overall response rates were also significantly increased (79% vs 66%

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doi: 10.1038/s12276-023-01013-0 86 CroizerHMhaidlyRKiefferYGentricGDjerroudiLLeclereRet al

Caspr2 autoantibodies disrupt the binding of caspr2 to contactin2, potentially interfering with the clustering of VGKC ay juxtaparanodes, resulting in hyperexcitability of peripheral nerves (66)