how does glp 1 affect dopamine GLP-1 Agonists Can Be Heaven or Hell Dependent Upon Dopaminergic Genetic/Epigenetic Antecedents[v1] Mechanisms of GLP-1 in Modulating

As with GLP-1 prior to the advent of long-acting analogs, incomplete translational tools may explain the gap between strong preclinical biology and equivocal human data

Im wondering if I should have just hung in there and that maybe it would have reversed over time(?), in case you have any real-world experience with this in patients

Li AQ, Zhao L, Zhou TF, Zhang MQ, Qin XM

Further Reading All GLP-1 Agonists Content Do GLP-1 Drugs Reduce Cancer Risk or Increase It

The drug had a half-life of about one week and stronger effects on glycaemia and body weight with mean reductions in HbA 1c of 18 mmol/mol and in body weight of 5.7 kg in the phase-III programme [20]

The underlying mechanisms involve both direct and indirect effects