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Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy

In a clinical trial, participants taking semaglutide weekly injections lost 15 percent of their body weight, on average

Advanced analytical techniques are enabling researchers to track the compound's effects on global metabolite profiles, revealing complex interactions between NAD+ metabolism, methylation cycles, and other metabolic pathways that were previously unappreciated

The study analyzed deficiency rates among different age groups

CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor

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