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Still other functions in GF animals, such as those affecting CNS serotonergic neurotransmission, cannot be restored by re-colonization by the age of weaning, suggesting that the window for microbial influence on these functions is already closed 56

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Abhishek Mittal is a PhD Scholar at Amity Institute of Public Health, Amity University, Noida, India

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In other in vitro and in vivo experiments, SH-SY5Y (human neuroblastoma) cells were incubated with 1-methyl-4-phenylpyridinium ion, and mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine were used to determine neuroprotection of schisantherin A