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However, the translation of NRF2 -targeted therapies from preclinical studies to clinical application remains limited

A cloudy or particulate solution from any compound is a sign to discard the vial

On this basis, we not only summarized the effect of ferroptosis in the pathophysiological process of IS, but also listed the corresponding drug targets and potential compounds, aiming to provide new therapeutic ideas for reducing post-stroke injury by targeting ferroptosis

The combination of DHA with cisplatin triggered cell death in pancreatic ductal adenocarcinoma (PDAC) by promoting the degradation of GPX4, creation of ROS and the degradation of ferritin, leading to induction of ferroptosis (Du J

, Peck BD, Wen Y, et al

A study by Wierdsma et al