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Under normal, healthy conditions, this receptor is physically blocked by a magnesium ion, preventing excessive excitatory signaling

This GSH-dependent conversion is one of the motivations for studying ascorbate-derived imaging agents, whose interconversion depends on both the concentration of GSH and the presence or absence of reactive oxygen species 14,15

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ISSN 1871-5125

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The 3 mg dose is intended for treatment initiation and is not effective for glycemic control