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Bielawska AE, Shapiro JP, Jiang L, Melkonyan HS, Piot C, Wolfe CL, et al
Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events
Results Integrated metabolic analysis of MYCdriven liver tumors To identify novel metabolic pathways that are altered in primary liver tumors with high MYC expression (Fig 1A), we performed mRNA expression and mass spectrometrybased metabolite profiling of LT2MYC tumor samples and nave LT2 liver controls (Fig 1B and Dataset EV1)
As such, GSH is commonly used in experimental frameworks investigating cellular aging, senescence markers, and stress-induced cellular dysfunction
Cells that maintain and repair the liver identified
