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A shift in the glutathione redox ratio towards the oxidised state may lead to decreased cell proliferation, DNA damage [44] and increased apoptosis [45] that could potentially affect neurological development in the early stages of life

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Given these inconsistencies, future research should focus on well-designed, large-scale RCTs that incorporate biomarker-guided stratification (e.g., SELENOP levels, GPx activity) to identify subgroups that would benefit most from selenium supplementation