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[DOI] [PubMed] [Google Scholar] [128].Chen X, Kang R, Kroemer G, et al

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These findings make it a useful compound for preclinical studies focused on lipid metabolism and mitochondrial efficiency

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For the generation of CRISPR-Cas9 KO HeLa cells, cells were transfected with pX459 plasmid coding for the gRNA against the gene of interest, as well as the puromycin resistance

High-quality clinical data from such studies will inform the development of clinical practice guidelines on HRT and MASLD, to guide counseling and informed decision-making for postmenopausal women and determine whether HRT has potential as a disease-modifying treatment for MASLD