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L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial

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Prostaglandin analogs

We studied mice with genetically altered PCC activity (FVB Pcca / A138T) 23 , wherein the murine Pcca gene was knocked out and a hypomorphic human mutant ( PCCA A138T) was inserted

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In a diet-induced obese mouse model, amkinone at 10 mg/kg/day dose showed improvement in glucose tolerance and insulin sensitivity concomitant with the reduction in adiposity and body weight without affecting food consumption
