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P., & Brosnan, M

Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation

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Panels that pair flux readouts (e.g., DHE2-OH-E for O 2 , compartment-targeted HyPer/roGFP-Orp for H 2 O 2 , peroxiredoxin redox state) with damage footprints (F-isoprostanes, carbonyls/nitrotyrosine, 8-oxoG) and iron/ferroptosis metrics (labile iron pool, oxidized phospholipids, GPX4 context) provide the attribution needed to separate signalling from injury, compare studies and titrate therapy