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Other malignancies, including urinary tract, stomach, and small intestine cancers, have also been linked to MSH6 mutations, though they occur less frequently (26)

GSH exerts antioxidant enzyme activity, which helps to inhibit ROS oxidative damage, regulating oxidative stress
Qi X, Ng KT, Shao Y, Li CX, Geng W, Ling CC, Ma YY, Liu XB, Liu H, Liu J, et al

doi: 10.1038/s41467-024-46971-9 49 RanCLiuHHitoshiYIsraelMA

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Thats when oxidative stress tips the balance
