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This genes mutations are believed to induce ASD pathology by affecting the chromatin-remodeling ChAHP [343] and SWItch/Sucrose Non-Fermentable (SWI/SNF) complexes [344, 345] during embryonic development

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bound LCACs within the perfusion buffer

Recent clinical metabolomics studies have provided direct evidence for this: compared with healthy controls, the levels of multiple metabolites in the Tryptophan-KP in the serum of newly diagnosed RA patients were significantly downregulated, and the levels of these metabolites were negatively correlated with disease activity indices(DAS28) and autoantibodies(anti-CCP) (Wu et al., 2025)

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