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Interestingly, the administration of Vitamin E, which has antioxidant properties, reduces MDA, SOD and GPX in hyperthyroid rats (26), and it seems also to be protective against a thyroxine-induced increase of lipid peroxidation in cardiac and skeletal muscles (27)

1995 doi: 10.1177/106002809502901213

This article presents the current state of knowledge on the role of lutein and zeaxanthin, especially from human studies targeting their metabolism and bioavailability, with recommendations to consume xanthophyll-rich foods

ii) a better typing of chronic users to study risks of developing hepatotoxicity at the highest recommended doses (even though this is still controversial there is accumulating evidence that the maximum recommended dose can induce mild-to-moderate hepatic cytolysis)

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