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PLoS One 14, e0210248

Hyperhomocysteinemia: Focus on Endothelial Damage as a Cause of Erectile Dysfunction

TRL remnants are a heterogeneous group of lipoproteins, with variable density and particle size (Figure 3)

Autophagy plays different roles at different stages of tumor formation, suggesting that targeting one or more key molecules may drive a switch in autophagy function

Although these results highlight a role for KU-57788-activated DRP1 in modulating the NRF2/SLC7A11/GSH axis, we cannot exclude the possibility that KU-57788 exerts its anti-tumor effects through additional parallel mechanisms

Indeed, copper can be found at the active site of many critical enzymes, including those essential for neurological function, such as the predominantly cytosolically localized antioxidant Cu, Zn superoxide dismutase (SOD1), the mitochondrial electron transport chain protein cytochrome c oxidase, and the secretory pathway enzymes dopamine -hydroxylase (DBH) and peptidylglycine -amidating monooxygenase (PAM) (Scheiber et al., 2014)