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Additionally, GBM maintains an immunosuppressive local microenvironment through a variety of signaling pathways, including the release of immunosuppressive cytokines (e.g., IL-6), the expression of immune checkpoint molecules (e.g., PD-L1), TGF-B signaling, and the expression of STAT3 [25,26,27,28,29,30]

DMSO applied at a concentration of 1% v/v for 48 h is toxic for human lens epithelial cells, effectively reducing their viability by promoting apoptosis and upregulating the apoptotic promoter Bax in these cells 18

used palbociclib to induce senescence in TNBC xenografted mice

A.AliM.ShukatR.HanifS.HassanM.et al (2024)

Nature Precedings

Joshi, N