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The application irinotecan-releasing benzoporphyrin and nitric oxide-releasing DOX loaded into a liposome-like nanoformulation was able to respectively reduce ABCG2 -mediated resistance and MRP1- and P-gp-mediated resistance (414, 415)

6J-O) demonstrated that Keap1 protein expression was significantly upregulated, while Nrf2 and GPX4 protein levels were downregulated in DSS-treated colonic tissues versus the Control group

M., Samelson, L

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Remethylation of homocysteine to methionine mediated by betaine occurs in the liver and kidney, whereas the vitamin B12-dependent pathway is present in most tissues [3]