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These challenges limit peptides clinical application and explain the interest in alternative routes of peptide administration, particularly nose-to-brain (N-to-B) delivery, which allows protein and peptide drugs to reach the brain noninvasively
Quelven I, Monteil J, Sage M, Saidi A, Mounier J, Bayout A, et al
B 12 levels ranged between 143 pg/mL and 177 pg/mL, and all three had an elevated MCV due to reticulocytosis
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