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For some individuals, especially children with autism or CFD, this combination can rapidly restore folate status in the central nervous system and may be used long-term as part of an integrative treatment plan

However, long-term safety data is limited, and its full risk profile is not yet completely understood

It is given as an intramuscular or subcutaneous injection under medical supervision

Warnings and Precautions 5.1 Myelosuppression and Increased Risk of Myelosuppression without Vitamin Supplementation ALIMTA can cause severe myelosuppression resulting in a requirement for transfusions and which may lead to neutropenic infection

And anyone with severe renal impairment should discuss both compounds with their physician before proceeding

"The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice"