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Previously, we showed that a population of OE19-parental (OE19-PT) cells could enter a DTP state to evade the strong selective pressure of a high concentration (500 nM) of lapatinib for 35 days, at which point the cells we able to resume proliferation demonstrating that they were not permanently growth-arrested [17]

The ultimate goal of future studies should be to combine CD4 + and CD8 + responses in vivo to activate DCs and T cells for a long period of time

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In necrosis, caspase activation is not necessary for cell death
