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This event results in mitochondrial swelling and impairment of the respiratory chain, thereby exacerbating oxidative stress-induced damage (71)

Leur accumulation exacerbe le stress oxydatif li , long terme, au vieillissement cellulaire

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It plays a crucial role in the systemic distribution of and exposure to lipophilic and amphipathic drugs, carcinogens, toxins, and other foreign substances [100]

SchultzDarken, N., Braun, K

and the SLC38 family, with a wide tissue distribution [50]