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Despite the uncertainties, interest appears to be growing, possibly influenced by the popularity of FDA-approved GLP-1 weight loss drugs

The signs and symptoms of the deficiency may include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections, and symptoms caused by problems in the brain including seizures, intellectual disability, and loss of coordination (ataxia)

[DOI] [PubMed] [Google Scholar] 81.Smith BM, Smith JM, Tsai JH

A., Mathew, A., Makkar, S

It is commonly studied in models involving soft tissue repair, gastrointestinal barrier integrity, inflammatory signaling, vascular response, and connective tissue remodeling

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