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doi: 10.1016/S0149-7634(00)00022-1 40 El-SakkaAI

Chivero ET, Guo ML, Periyasamy P, Liao K, Callen SE, Buch S

A 2012 study demonstrated that CFH Y402H, mentioned above as conferring an increased risk of AMD development, binds peroxidized phospholipids and initiates complement activity, suggesting a connection between the long-studied complement system and lipid peroxidation [172, 173]

The morphological changes in seminiferous tubules were assessed using immunostaining for DDX4 and SYCP3 (Fig

Thus, it is clear from these studies that several pathways become activated in TCE-sensitized mice, and these are then linked to renal injury by activating pathological processes such as oxidative stress, release of proinflammatory cytokines, and mitochondrial damage

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