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However, there are two patented active ingredients that stabilise the methylfolate and thus drastically increase bioavailability

If B12 levels are low but still in range indicating a functional deficiency (this is a deficiency but blood tests appear in normal range) then second line testing of homocysteine and MMA can confirm B12 and/or folate deficiency

Its the same area where youd get a flu shot

Spinal cord damage Spinal cord damage, known as myelopathy (problem with the spinal cord), is also associated with vitamin B12 deficiency

Laboratory interference: Persistent unexplained elevation may reflect macro-B12 (immunoglobulin-bound B12) or other assay interferences

Figure 5 3.4 Safety and tolerability of the B12 supplements All the B12 supplements were generally well tolerated by all participants in the three studies