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If you have been taking methylfolate, methylcobalamin, and P5P in the right forms and doses for three months and the symptom has not improved, the symptom is probably not being driven by MTHFR

Although the effective drugs that can inhibit epileptogenesis are yet to be discovered, minimizing inflammatory reactions in the brain neurons can be a reasonable potential strategy against epilepsy [2]

observed that 21 patients who presented with other primary findings of vitamin B12 deficiency also had hyperpigmentation [9]

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Le Guellec, S

Wiberg G