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[DOI] [PubMed] [Google Scholar] 102.Ogawa K., Hirose S., Nagaoka S., Yanase E

Dahl, W

Concentration, total formulation composition, pharmacy reputation, and cost matter more for most users

doi: 10.1007/s43630-023-00378-5

By mapping Chr21, the APP gene encodes the amyloid precursor protein and the EST2 gene encodes a transcription factor that further promotes the expression of APP , resulting in increased production of A oligomeric toxic peptides, which form the backbone of amyloid plaques (463)

This inflammatory process is characterized by the activation of resident glial cells, the release of proinflammatory cytokines and chemokines, and the recruitment and infiltration of peripheral cells into the CNS as a consequence of the breakdown of the blood-brain barrier (Kelly et al., 2020)